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Publications


Journal Publications
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Deep learning for psychiatric genomics: from tools to applications  πŸ“„
Junhao Liu, Siwei Xu, Dongbo Sun, Chaoyang Wang, Jing Zhang
Current Opinion in Genetics & Development
2026
Central amygdala single-nucleus atlas reveals chromatin and gene transcription dynamics in human alcohol use disorder  πŸ“„
Che Yu Lee et al.
Nature Communications
2026
Transcriptomic and Chromatin Dynamics of the Human PTSD Brain at Single Cell Resolution  πŸ“„
Matthew Girgenti et al.
European Neuropsychopharmacology
2025
Combined single-cell profiling of chromatin–transcriptome and splicing across brain cell types, regions and disease state  πŸ“„
Wen Hu et al.
Nature Biotechnology
2025
Single cell transcriptomic and chromatin dynamics of the human PTSD brain  πŸ“„
Ahyeon Hwang et al.
Nature
2025
Single-cell genomics and regulatory networks for 388 human brains  πŸ“„
Prashant S Emani et al.
Science
2024
scENCORE: leveraging single-cell epigenetic data to predict chromatin conformation using graph embedding  πŸ“„
Ziheng Duan et al.
Briefings in Bioinformatics
2024
Translator: A Transfer Learning Approach to Facilitate Single-Cell ATAC-Seq Data Analysis from Reference Dataset  πŸ“„
Siwei Xu et al.
Journal of Computational Biology
2022
InsuLock: A Weakly Supervised Learning Approach for Accurate Insulator Prediction, and Variant Impact Quantification  πŸ“„
Shushrruth Sai Srinivasan et al.
Genes
2022
Integrating longitudinal clinical and microbiome data to predict growth faltering in preterm infants  πŸ“„
Jose Lugo-Martinez et al.
Journal of Biomedical Informatics
2022

Conference Publications
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Multimodal Cell Context Instruction Tuning for Conditional DNA Regulatory Sequence Generation with Large Language Models  πŸ“„
Junhao Liu et al.
IEEE International Conference on Image Processing (ICIP)
2025
CytoFlow: A Novel Computational Method to Construct Signal Transduction Networks at Single-Cell Resolution based on Flow Networks  πŸ“„
Yi Dai, Ziheng Duan, Siwei Xu, Jing Zhang
IEEE International Conference on Medical Artificial Intelligence (MedAI)
2024
Understanding Transcriptional Regulatory Redundancy by Learnable Global Subset Perturbations  πŸ“„
Junhao Liu et al.
Asian Conference on Machine Learning (ACML)
2024
iHAST: Integrating Hybrid Attention for Super-Resolution in Spatial Transcriptomics  πŸ“„
Xi Li, Jing Zhang, Ziheng Duan, Yi Dai, Siwei Xu
British Machine Vision Conference (BMVC)
2024
Learnable Subset Perturbations for Understanding Transcriptional Regulatory Redundancy  πŸ“„
Junhao Liu, Siwei Xu, Dylan Riffle, Ziheng Duan, Jing Zhang
NeurIPS 2024 Workshop on Data-driven and Differentiable Simulations, Surrogates, and Solvers
2024
scACT: Accurate Cross-modality Translation via Cycle-consistent Training from Unpaired Single-cell Data  πŸ“„
Siwei Xu, Junhao Liu, Jing Zhang
ACM International Conference on Information and Knowledge Management (CIKM)
2024
iMIRACLE: An Iterative Multi-View Graph Neural Network to Model Intercellular Gene Regulation From Spatial Transcriptomic Data  πŸ“„
Ziheng Duan, Siwei Xu, Cheyu Lee, Dylan Riffle, Jing Zhang
ACM International Conference on Information and Knowledge Management (CIKM)
2024

Consortium Publications
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The single-cell opioid responses in the context of HIV (SCORCH) consortium  πŸ“„
SCORCH Consortium
Molecular Psychiatry
2024
Transcriptomic sex differences in postmortem brain samples from patients with psychiatric disorders  πŸ“„
PsychENCODE Consortium
Science Translational Medicine
2024
Single-cell multi-cohort dissection of the schizophrenia transcriptome  πŸ“„
PsychENCODE Consortium
Science
2024
A data-driven single-cell and spatial transcriptomic map of the human prefrontal cortex  πŸ“„
PsychENCODE Consortium
Science
2024
Massively parallel characterization of regulatory elements in the developing human cortex  πŸ“„
PsychENCODE Consortium
Science
2024
Cross-ancestry atlas of gene, isoform, and splicing regulation in the developing human brain  πŸ“„
PsychENCODE Consortium
Science
2024
Using a comprehensive atlas and predictive models to reveal the complexity and evolution of brain-active regulatory elements  πŸ“„
PsychENCODE Consortium
Science Advances
2024
Evaluating performance and applications of sample-wise cell deconvolution methods on human brain transcriptomic data  πŸ“„
PsychENCODE Consortium
Science Advances
2024

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